Comparing Different Normal Tissue Complication Probability (NTCP) Models of Radiation-Induced Temporal Lobe Injury after Intensity-Modulated Radiation Therapy for Nasopharyngeal Carcinoma
نویسندگان
چکیده
منابع مشابه
LASSO-based NTCP model for radiation-induced temporal lobe injury developing after intensity-modulated radiotherapy of nasopharyngeal carcinoma
We investigated the incidence of temporal lobe injury (TLI) in 132 nasopharyngeal carcinoma (NPC) patients who had undergone intensity-modulated radiotherapy (IMRT) in our hospital between March 2005 and November 2009; and identified significant dosimetric predictors of TLI development. Contrast-enhanced lesions or cysts in the temporal lobes, as detected by magnetic resonance imaging (MRI), we...
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Background: To investigate a method for standardizing intensity modulated radiation therapy (IMRT) optimization for nasopharyngeal carcinoma (NPC), in order to reduce the influence of subjective factors. Materials and Methods: This study is based on example IMRT plans for NPC, which were randomly divided into data acquisition and data verification groups. Organs at risk (OARs) were analyzed for...
متن کاملRadiation-Induced Temporal Lobe Injury for Nasopharyngeal Carcinoma: A Comparison of Intensity-Modulated Radiotherapy and Conventional Two-Dimensional Radiotherapy
BACKGROUND To compare the radiation-induced temporal lobe injury (TLI) in patients with nasopharyngeal carcinoma (NPC) treated with intensity-modulated radiotherapy (IMRT) or two-dimensional conventional radiotherapy (2D-CRT). PATIENTS AND METHODS 1276 cases of NPC treated with IMRT or 2D-CRT were retrospectively reviewed. A diagnosis of TLI was made on follow-up magnetic resonance imaging (M...
متن کاملNormal tissue complication probability modeling for cochlea constraints to avoid causing tinnitus after head-and-neck intensity-modulated radiation therapy
BACKGROUND Radiation-induced tinnitus is a side effect of radiotherapy in the inner ear for cancers of the head and neck. Effective dose constraints for protecting the cochlea are under-reported. The aim of this study is to determine the cochlea dose limitation to avoid causing tinnitus after head-and-neck cancer (HNC) intensity-modulated radiation therapy (IMRT). METHODS In total 211 patient...
متن کاملRadiobiological Model-Based Comparison of Three-Dimensional Conformal and Intensity-Modulated Radiation Therapy Plans for Nasopharyngeal Carcinoma
Introduction: Radiobiological modeling of radiotherapy plans are used for treatment plan comparisons. The current study aimed to compare the three-dimensional conformal radiation therapy (3DCRT) and intensity-modulated radiation therapy (IMRT) plans for nasopharyngeal cancer using radiobiological modeling. Materials and Methods: This study was conducted on 10 patients with nasopharyngeal carci...
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ژورنال
عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics
سال: 2019
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2019.06.1579